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IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE249638
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We performed a comprehensive transcriptomic profiling of BM-infiltrating CD4+ T cells of AML patients from different AML patients and controls. This analysis revealed that BM-infiltrating CD4+ T cells are activated and skewed towards Th1 polarization. We characterized the molecular signature of BM-infiltrating CD4+ T cells in patients with acute myeloid leukemia (AML) compared to control subjects.
创建时间:
2024-09-01
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