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Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a transcriptional repressor (CymR) derived 10 amino acid peptide

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Protein Data Bank Japan2025-05-28 更新2026-04-19 收录
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Crystal structure of O-acetyl-L-serine sulfhydrylase A (CysK) from Staphylococcus aureus NCTC 8325 complexed with a transcriptional repressor (CymR) derived 10 amino acid peptide Descriptor: Cysteine synthase, Transcriptional repressor (CymR) derived 10 amino acid peptide Authors: Pederick, J.L, Vandborg, B.C, Bruning, J.B. Deposit date: 2023-05-07 Release date: 2024-11-13 Last modified: 2025-05-28 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Identification of Cysteine Metabolism Regulator (CymR)-Derived Pentapeptides as Nanomolar Inhibitors of Staphylococcus aureus O -Acetyl-l-serine Sulfhydrylase (CysK). Acs Infect Dis., 11, 2025

金黄色葡萄球菌NCTC 8325来源的O-乙酰-L-丝氨酸巯基酶A(CysK)与转录阻遏蛋白(CymR)衍生10氨基酸肽形成复合物的晶体结构 描述项:半胱氨酸合酶、转录阻遏蛋白(CymR)衍生10氨基酸肽 作者:Pederick, J.L、Vandborg, B.C、Bruning, J.B. 存档日期:2023-05-07 发布日期:2024-11-13 最后修改日期:2025-05-28 实验方法:X射线衍射(分辨率1.32 Å) 引用文献:《半胱氨酸代谢调控因子(CymR)衍生五肽作为金黄色葡萄球菌O-乙酰-L-丝氨酸巯基酶(CysK)的纳摩尔级抑制剂的鉴定》,《ACS Infectious Diseases》,第11卷,2025年
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2023-05-07
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