Crystal structure of HLA-A*11:01 in complex with KRAS G12S 10-mer peptide (VVVGASGVGK)
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Crystal structure of HLA-A*11:01 in complex with KRAS G12S 10-mer peptide (VVVGASGVGK) Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... Authors: Jiali, Z, Linlin, Z. Deposit date: 2025-09-19 Release date: 2025-12-24 Last modified: 2026-01-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure guided analysis of KRAS G12 mutants in HLA-A*11:01 reveals a length encoded immunogenic advantage in G12D. Commun Biol, 9, 2025
人类白细胞抗原A*11:01(HLA-A*11:01)与Kirsten大鼠肉瘤病毒癌基因同源物(KRAS)G12S十肽(VVVGASGVGK)结合的晶体结构 描述:β2-微球蛋白(β2-microglobulin)、HLA I类组织相容性抗原Aα链等 作者:Z贾利、Z林琳 存档日期:2025-09-19 发布日期:2025-12-24 最后修改日期:2026-01-21 检测方法:X射线衍射(2.8埃) 引用文献:《HLA-A*11:01中KRAS G12突变体的结构导向分析揭示G12D的长度编码免疫原性优势》,Commun Biol,9卷,2025年
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2025-09-19



