References that support the parameters are given where available. The entry rates into LNs and spleen are not experimental estimates but are adopted from earlier modeling work [17]. However, these val
Differentiation of CD4+ T cells into effector or regulatory phenotypes is tightly controlled by the cytokine milieu, complex intracellular signaling networks and numerous transcriptional regulators. W
Values are approximated within biologically relevant ranges, based on known immune system characteristics and previous modeling work [8], [14] (see Appendix S1 for details). Although the exact phase d
HTML version of the R markdown file containing all code necessary to reproduce the results presented in the main text, as well as to produce supplemental figures.
