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Genome-wide Expression Profiling in Peripheral Models of XDP

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74068
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We performed genome-wide expression profiling using an Agilent microarray in blood- and fibroblast-derived samples from XDP patients and ethnicity-matched Filipino controls. The hypothesis was that TAF1 is dysregulated in peripheral models of XDP and this dysregulation has a concomitant downstream effect on expression genome-wide. Cross-sectional, XDP affecteds vs controls. In blood-derived RNA: 10 from affecteds, 12 from controls. In fibroblast-derived RNA: 15 from affecteds, 10 from controls
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2018-01-09
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