Human milk oligosaccharides impact cellular and inflammatory gene expression and immune cell composition

NIAID Data Ecosystem2026-03-13 收录

母乳低聚糖免疫调节

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https://www.ncbi.nlm.nih.gov/sra/SRP363455 数据链接链接失效反馈

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资源简介：

Direct effect of human milk oligosaccharides on gastrointestinal tract metabolism and immune system even in the absence of host microbiota.

创建时间：

2022-03-15

Equilibrative Nucleoside Transporter 3 is an IFN-stimulated Gene that Facilitates Viral Genome Release

病毒-宿主相互作用

免疫代谢

An increasing body of evidence emphasizes the role of metabolic reprogramming in immune cells to fight off infections. However, little is known about the regulation of metabolite transporters that fac

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DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip

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PD-1联合治疗

IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s

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Mannose remodels glucose metabolism to antagonize the overwhelming host inflammatory response

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病毒感染代谢干预

we performed transcriptomic analysis in A549 cells and demonstrated a reduced proinflammatory response but increased host tolerance upon H1N1 virus infection and mannose therapy, providing further evi

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D- 2-hydroxyglutarate is an immunometabolite that accumulates in macrophages after TLR activation and inhibits inflammatory responses

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巨噬细胞炎症抑制

Macrophages undergo extensive metabolic rewiring upon activation and this serves many roles beyond the production of energy and anabolic building blocks. So-called immunometabolites that accumulate up

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Requirement of mitochondrial transcription factor A in interleukin-17-producing gdT cells to regulate the small intestine homeostasis and metabolism. Requirement of mitochondrial transcription factor A in interleukin-17-producing gdT cells to regulate the small intestine homeostasis and metabolism

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小肠稳态调节

Interleukin 17 (IL-17)-producing gamma delta T (gdT17) cells are one of the major cellular sources of IL-17 under the steady state and in disease. However, gdT17 cell metabolism and its role in tissue

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Human milk oligosaccharides impact cellular and inflammatory gene expression and immune cell composition

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