Crystal structure of SARS-CoV-2 main protease (Mpro) in complex with covalent inhibitor A02

Crystal structure of SARS-CoV-2 main protease (Mpro) in complex with covalent inhibitor A02 Descriptor: 1-[(1M)-1-(3-methoxyphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]ethan-1-one, 3C-like proteinase nsp5 Authors: D'Oliviera, A, Mugridge, J.S. Deposit date: 2024-11-08 Release date: 2026-05-13 Last modified: 2026-05-27 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A Novel Covalent Inhibitor Fragment for the SARS-CoV-2 Main Protease Identified by Target-Specific Deep Learning. Acs Chem.Biol., 21, 2026