Single-cell RNA sequencing was performed on bone marrow mononuclear cells of a patient with acute myeloid leukemia with erythroid differentiation of the blasts and on peripheral blood mononuclear cell

NIAID Data Ecosystem60

scRNA seq data from AML PDXs throughout a cytarabine treatment, and directly from AML patients at differnet stages of disease progression

急性髓系白血病转录组学

肿瘤治疗响应

We used scRNA seq on regenerating PDX models and de novo AML patient cells to delineate the heirarchical regeneration of AML following treatment Overall design: Bone Marrow from AML PDXs were isolated

NIAID Data Ecosystem50

Engineering CAR-NK cells to secrete IL15 sustains their anti-AML functionality, but is associated with systemic toxicities

CAR-NK细胞疗法

急性髓系白血病转录组学

Chronic stimulation with Acute Myeloid Leukemia can induce dysfunction in NK and CAR-NK cells. We evaluated transcriptomic differences on the day 10 of chronic antigen stimulation in NK cells secretin

NIAID Data Ecosystem60

RNA-seq in 73 B-lineage ALL patients. RNA-seq in 73 B-lineage ALL patients

急性髓系白血病转录组学

药物敏感性关联分析

RNA-seq from RNA isolated from bone marrow or peripheral blood of newly diagnosed acute lymphoblastic leukemia patients on TotalXVI protocol Overall design: LC50 determination performed with concordan

NIAID Data Ecosystem50

RNA sequencing of MOLM-13 and KG-1a cell lines after inhibition of S100A9 and BCL2

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