Summary of effects on genome stability for genes depleted with siRNA using HR and centrosome assay on HeLa cells.

√: Decreased HR activity (less than 80% of HR activity of negative control sample) or supernumerary centrosome phenotype was observed in the cell with target gene depletion. ×: No effect observed on cells with target gene depletion. ND: not determined. ?: Decreased HR activity may be due to plasmid transfection inefficiency. Lethal: the depletion is lethal to cells.