Analysis of simulated disease architecture with 180 causal 1Mbp loci yielding a true . In each locus, 1–10 causal variants were sampled from either low-frequency () of common (MAF) WTCCC2 SNPs. For ea
The presence of mutations in glucocerebrosidase (GBA) gene is a known factor increasing the risk of developing Parkinson’s disease (PD). Mutations carriers have earlier disease onset and are more like
