Structural gene substitution rate variation among viruses with different cell tropisms.

The significance of viruses with each target cell in the left column having higher log-scale mean substitution rates than the viruses with each target cell in the top row is designated with a p-value from a one-tailed t-test. The threshold for statistical significance (α = 0.01) was Bonferroni-corrected to account for multiple comparisons (P<0.001); the significant values are bolded. N = neurons, En = endothelial cells, L = leukocytes, H = hepatocytes, Ep = epithelial cells.