SNP genotyping in HS mice.

Genomic location is given based on mouse genome assembly NCBI build 37. Details of the Sod1 and Il1-r1 SNPs are available from the Sanger Centre (www.sanger.ac.uk/cgi-bin/modelorgs/mousegenomes/snps.pl). All polymorphisms were analysed by allele discrimination using a 7500 Fast real time PCR system (Applied Biosystems). For probe details see Table S1. For all genotypes, the statistical test used was the Kruskal-Wallis non-parametric ANOVA. The allelic test used was the Mann-Whitney test.