Synthesis of Pyrido-Fused Quinazolinone Derivatives via Copper-Catalyzed Domino Reaction
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https://figshare.com/articles/dataset/Synthesis_of_Pyrido_Fused_Quinazolinone_Derivatives_via_Copper_Catalyzed_Domino_Reaction/2074771
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资源简介：
A simple and efficient synthesis
of 11H-pyrido[2,1-b]quinazolin-11-ones
by Cu(OAc)2·H2O-catalyzed reaction of easily
available substituted isatins and
2-bromopyridine derivatives has been developed. The reaction involves
C–N/C–C bond cleavage and two C–N bond formations
in a one-pot operation. This methodology is complementary to previously
reported synthetic procedures, and two plausible reaction mechanisms
are discussed.
创建时间：
2016-02-12
