Paired Metabolomic and Transcriptomic Time Series of Streptomyces coelicolor M145 Secondary Metabolism

We utilized weighted correlation networking analysis to integrate metabolite and transcription data. We demonstrate the effectiveness of this strategy and identify potential regulatory effects on biosynthetic gene clusters. Overall design: Examination of mRNA and Secondary metabolite levels of Streptomyces coelicolor M145 over an eight day time course in ISP2 media. Collected in biological triplicate