Cell competition is a tumor suppressor mechanism in the thymus.
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Cell competition is a tumor suppressor mechanism in the thymus.
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2014-05-16
相关数据集
Distinct modes of cell competition shape mammalian tissue morphogenesis. Distinct modes of cell competition shape mammalian tissue morphogenesis
Cell competition (CC)—the sensing and elimination of less fit “loser” cells by neighbouring “winner” cells—was first described in Drosophila. Although proposed as a selection mechanism to optimize tis
NIAID Data Ecosystem90
Gene expression profile of cells with unfit Wnt morphogen gradient during cell competition
Morphogen signalling forms an activity gradient and instructs cell identities in a signalling strength-dependent manner to pattern developing tissues. However, developing tissues also undergo dynamic
NIAID Data Ecosystem50
Autocrine glutamate signaling drives cell competition in Drosophila
Cell competition is an evolutionary conserved quality control process that eliminates suboptimal or potentially dangerous cells. Although differential metabolic states act as direct drivers of competi
Mendeley Data30
Gene expression signatures of MDCK-pTR GFP-RasV12 mCherry-β-catenin Δ131 cells cultured alone or mixed with MDCK mCherry-β-catenin Δ131 cells. Gene expression signatures of MDCK-pTR GFP-RasV12 mCherry-β-catenin Δ131 cells cultured alone or mixed with MDCK mCherry-β-catenin Δ131 cells
Normal epithelial cells exert their competitive advantage over RasV12-transformed cells and eliminate them into apical lumen via cell competition. However, it remains elusive which internal or externa
NIAID Data Ecosystem80
Competition between hematopoietic stem and progenitor cells controls the hematopoietic stem cell homeostasis [bulk RNA-seq]
Cellular competition for limiting hematopoietic factors is a physiologically regulated but poorly understood process. Here, we studied this phenomenon by hampering hematopoietic progenitor access to L
NIAID Data Ecosystem30



