five

Targeted sequencing of brain expressed miRNA genes

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https://www.omicsdi.org/dataset/ega/EGAS00001001607
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As regulators of gene expression, microRNAs (miRNAs) are likely to play an important role in the development of disease. In this study we present a large-scale strategy to identify miRNAs with a role in the regulation of neuronal processes by screening 289 brain expressed miRNAs. Thereby we found variant rs7861254 located near the MIR204 gene to be significantly associated with schizophrenia. This variant resulted in reduced expression of miR-204 in neuronal-like SH-SY5Y cells.EGA study EGAS00001001607
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2017-07-26
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