ChIP-seq of adenovirus core protein VII

To determine whether adenovirus core protein VII preferentially binds specific host chromatin regions, we performed native chromatin immunoprecipitation of protein VII-bound chromatin followed by next-generation sequencing (ChIP-seq).为明确腺病毒核心蛋白VII（adenovirus core protein VII）是否优先结合特定宿主染色质区域，我们对结合了蛋白VII的染色质开展原生染色质免疫沉淀实验，随后进行下一代测序（ChIP-seq）分析。