BuDDI analysis of sciplex3 data
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In this zipped folder are two folders: data and resultsThe sciplex data used in all of the sciplex3 analyses were downloaded from https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM4150378, presented in this paper: DOI: 10.1126/science.aax6234datadata contains one subfolders: single_cell_datasingle_cell_data has the processed single-cell data and the generated pseudobulks used by BuDDI. Within this folder,augmented_sciplex_data contains the pseudobulkscibersort_sciplex contains the CIBERSORTx resultssciplex contains the processed sciplex dataresultsThis folder contains several results folders. Each one is specific to an experiment and a model. The naming convention is "model_CellLine". Each model learns all the drug embeddings together.buddiM2: the BuDDI modelbp: BayesPrismCVAE: conditional Variational AutoencoderPCA: principal components analysis



