Differential stability of task variable representations in retrosplenial cortex

Cortical neurons store information across different timescales, from seconds to years. Although information stability is variable across regions, it can vary within a region as well. Association areas are known to multiplex behaviorally relevant variables, but the stability of their representations is not well understood. Here, we longitudinally recorded the activity of neuronal populations in the mouse retrosplenial cortex (RSC) during the performance of a context-choice association task. We found that the activity of neurons exhibits different levels of stability across days. Using linear classifiers, we quantified the stability of three task-relevant variables. We find that RSC representations of context and trial outcome display higher stability than motor choice, both at the single cell and population levels. Together, our findings show an important characteristic of association areas, where diverse streams of information are stored with varying levels of stability, which may balan..., , , This README.txt file was generated on 2024-08-10 by Luis M. Franco

GENERAL INFORMATION

1. Title of Dataset: Differential Stability of Task Variable Representations in Retrosplenial Cortex
2. Author Information
A. Principal Investigator Contact Information
Name: Michael J. Goard
Institution: University of California Santa Barbara (UCSB)
Address: 6131 Biological Science Building II, University of California Santa Barbara (UCSB), Santa Barbara, CA 93106-5060
Email: [[e-mail]](mailto:[e-mail])

B. Associate or Co-investigator Contact Information
Name: Luis M. Franco
Institution: University of Oregon (UO)
Address: Institute of Neuroscience, University of Oregon (UO), 1254 University of Oregon, Eugene, OR 97403-1254
Email: [[e-mail]](mailto:[e-mail])
3. Date of data collection: stabilityData.mat ---> 2018-09-11 to 2019-06-14
exampleExperiment [folder] ---> 2018-09-11 to 2018-09-15
4. ...