JAK1 kinase (JH1 domain) in complex with povorcitinib
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JAK1 kinase (JH1 domain) in complex with povorcitinib Descriptor: 1,2-ETHANEDIOL, 4-{3-(cyanomethyl)-3-[(4M)-3',5'-dimethyl-1H,1'H-[4,4'-bipyrazol]-1-yl]azetidin-1-yl}-2,5-difluoro-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzamide, DIMETHYL SULFOXIDE, ... Authors: Epling, L.B, Fenalti, G. Deposit date: 2026-01-30 Release date: 2026-06-10 Last modified: 2026-06-17 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune Diseases. J.Med.Chem., 69, 2026
创建时间：
2026-01-30
