Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A12 Fab Heavy Chain, ... Authors: Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. Deposit date: 2021-05-17 Release date: 2021-09-15 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.32 Å) Cite: Structural insights into hepatitis C virus receptor binding and entry. Nature, 598, 2021

与绒猴CD81（tamarin CD81）结合的丙型肝炎病毒包膜糖蛋白2核心胞外域（ectodomain）结构
配体描述：2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose）、2A12 抗原结合片段（Fab）重链（2A12 Fab Heavy Chain）等
作者：Kumar A、Hossain RA、Yost SA、Bu W、Wang Y、Dearborn AD、Grakoui A、Cohen JI、Marcotrigiano J
提交日期：2021-05-17
发布日期：2021-09-15
最后修改日期：2024-10-09
实验方法：X射线衍射（分辨率3.32埃）
引用文献：《丙型肝炎病毒受体结合与入侵的结构学洞察》，发表于《自然》（*Nature*）598卷，2021年