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In vitro XO inhibitory potency of thiazolidine-2-thione derivatives.

Figshare2022-05-18 更新2026-04-28 收录

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https://figshare.com/articles/dataset/_i_In_vitro_i_XO_inhibitory_potency_of_thiazolidine-2-thione_derivatives_/19788656 数据链接链接失效反馈

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In vitro XO inhibitory potency of thiazolidine-2-thione derivatives.

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2022-05-18

结构生物学

黄嘌呤氧化酶抑制剂

Urate oxidase aza-xanthine complex in cyanide Descriptor: 8-AZAXANTHINE, SODIUM ION, Uricase Authors: Gabison, L, Prange, T, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M. Deposit date: 2007-12-06 R

Protein Data Bank Japan2023-11-01 更新80

Xanthine Oxidase Mediates Axonal and Myelin Loss in a Murine Model of Multiple Sclerosis

多发性硬化病理机制

黄嘌呤氧化酶抑制剂

ObjectivesOxidative stress plays an important role in the pathogenesis of multiple sclerosis (MS). Though reactive oxygen species (ROS) are produced by various mechanisms, xanthine oxidase (XO) is a m

Figshare2016-01-18 更新40

A patent review of xanthine oxidase inhibitors (2021–present)

黄嘌呤氧化酶抑制剂

痛风药物研发

Xanthine oxidase (XO) catalyzes the oxidation of both hypoxanthine and xanthine in the last two steps of the purine metabolic pathway, serving as a rate-limiting enzyme for uric acid production as wel

Taylor & Francis Group2024-12-30 更新30

Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor

结构生物学

黄嘌呤氧化酶抑制剂

Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor Descriptor: CALCIUM ION, CARBONATE ION, FE2/S2 (INORGANIC) CLUSTER, ... Authors: Eger, B.T, Okamoto

Protein Data Bank Japan2023-08-30 更新50

Novel Isoidide Subunit-Containing Xanthine Oxidase Inhibitors with Potent Hypouricemic Effects

痛风药物研发

黄嘌呤氧化酶抑制剂

Gout is one of the most common inflammatory arthritic diseases. Clinically, the need for safer and more effective xanthine oxidase (XO) inhibitors remains unmet. Here, a novel series of isoidide subun

Figshare2025-11-28 更新40

In vitro XO inhibitory potency of thiazolidine-2-thione derivatives.

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