BGISEQ-500 sequencer first reference dataset

BGISEQ-500 sequencer is a new desktop sequencer developed by BGI. Using DNA nanoballs (DNB) and combinational probe-anchor synthesis (cPAS) developed from Complete Genomics(TM) sequencing technology, it generates short reads at a large scale, which can help fulfill the growing demands for sequencing. Here, we present the first human whole genome sequencing dataset from the BGISEQ-500. The dataset was generated by sequencing the widely used Genome in a Bottle Consortium cell line, HG001 (NA12878) in one sequencing run. And the sequencing data were ~1,000 million paired sequences with the length of 50 bp (PE50). We also include examples of the raw images from the sequencer for reference. Finally, we carried out variation calling based on the dataset and compared it that identified from similar amount of publicly available HiSeq2500 data and the previously identified high confident variations.