Copper-Mediated α‑Trifluoromethylation of N‑Phenylcinnamamides Coupled with Dearomatization: Access to Trifluoromethylated 1‑Azaspiro[4.5]decanes

Copper-mediated intramolecular trifluoromethylation of N-phenylcinnamamides coupled with cyclization and dearomatization was used to construct various trifluoromethylated 1-azaspiro[4.5]­decanes in moderate to high yields and with excellent regioselectivity and diastereoselectivity.