The evolution of two transmissible cancers in Tasmanian devils (2023).. The evolution of two transmissible cancers in Tasmanian devils (2023).

Tasmanian devils have spawned two transmissible cancer lineages, named devil facial tumour 1 (DFT1) and devil facial tumour 2 (DFT2). We investigated the genetic diversity and evolution of these clones by deep whole genome sequencing of biopsies from 63 DFT1s, 39 DFT2s, 1 non-transmissible carcinoma and a panel of normal tissues from 72 animals. The here provided sequences were generated using Illumina XTen (150 BP paired-end) and are mapped to the newly assembled chromosome-level Tasmanian devil reference mSarHar1.11. For use of these resources, please cite: The evolution of two transmissible cancers in Tasmanian devils (Stammnitz et al. 2023, Science 380:6642)