Sensitivity and specificity of confirmed leads.

Cut-offs that had been optimised on the cohort 2 sample set using R&D batches of protein were applied to the results of assays of the cohort 1 samples to validate sensitivity (sens) and specificity (spec) for each confirmed lead alone (bold) and in combination with the eCDT-Lung R&D panel (italic). Sensitivity and specificity values are also given for every combination of two or three confirmed leads in when added to the eCDT-Lung R&D panel.