Effect of microtopography-induced nuclear constriction on gene expression in mesenchymal stromal cells in growth and osteogenic differentiation conditions I

To investigate the influence of microtopography-induced constriction of cell nuclei on gene expression in human mesenchymal stromal cells (hMSCs) Overall design: We then performed differential gene expression analysis using data obtained from RNA-seq data for hMSCs cultured on flat and micropillar surfaces.