The proposed method uses enriched de novo motifs on the peak sequences of Ago2-CLIP to determine miRNA-RNA heteroduplex for either canonical or non-canonical miRNA-binding sites. miRNA-RNA heteroduple
Non-chimeric crosslinks of Ago2 in mouse thymocytes, from miR181-eCLIP experiment in Verheyden & Klostermann et al 2024. Merge of all 3 replicates, crosslinks from plus strand.