Search for signatures of recent selection in human populations.
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SNP data (approx. 100 kbp up- and downstream of the GPR34/GPR82 genomic position) from HapMap database (Phase II) [35] individuals (CEU: European, HCB: Chinese, YRI: African) and a local Sorbs cohort [20], retrieved from a 500 K Affymetrix GeneChip were analyzed for signatures of recent selection (for details see Materials and Methods). Because the SNP data of HCB were almost monomorph, the ancestral sequence was defined by comparison with the respective sequence of the chimpanzee and included in the analyses.#A 10-kbp genomic fragment of the GPR34/GPR82 genomic region was amplified from 50 male individuals (23 Asians, 27 African individuals) (for details see Materials and Methods) and analyzed for signatures of recent selection.*P**P
创建时间：
2015-12-02
