GNPS - carmaphycin liver microcosm metabolism

NIAID Data Ecosystem2026-03-14 收录

代谢动力学

肝脏类器官代谢

数据链接：

https://www.omicsdi.org/dataset/gnps/MSV000091365 数据链接链接失效反馈

官方服务：

资源简介：

Standards of carmaphycin analogs and time series samples of liver microcosm metabolism

创建时间：

2023-02-25

Perspective on high-throughput bioanalysis to support in vitro assays in early drug discovery: Supplementary tables

高通量生物分析

代谢动力学

As the desire for a shortened design/make/test/learn cycle increases in early drug discovery, the pressure to rapidly deliver drug metabolism pharmacokinetic data continues to rise. From a bioanalytic

DataCite Commons2024-05-16 更新90

Apparent enzyme kinetic parameters for 4-OH-Cy formation by different microsome batches with recombinant CYP2B6*1 and different POR/CYP ratios.

代谢动力学

细胞色素P450酶活性

* POR measured as Cytochrome c reductase activity as in Table 1** Vmax is based on 4-OH-Cy formedCLint Calculated as Vmax/KmCyclophosphamide at different concentrations was incubated in 2 independent

Figshare2015-12-03 更新30

Pharmacokinetic data for CYP3A4 probe substrates in healthy Humans.

代谢动力学

种族差异药理学

This dataset contains all extracted informations used in the article "Inter-ethnic differences in CYP3A4 metabolism: A Bayesian meta-analysis for the refinement of uncertainty factors in chemical risk

NIAID Data Ecosystem20

CEFSULODIN LC/MS/MS DATA

代谢动力学

抗生素分布

Plasma and brain concentration profiles following IP administration of 100 mg/kg cefsulodin in C57BL/6J mice.

Mendeley Data70

Serum alcohol levels after the continuous infusion.

代谢动力学

药理毒理实验分析

Data presented as means ± SE (n = 3–6/group) and compared by one-way ANOVA and SNK method. *p<0.05 vs. 5 h group.

NIAID Data Ecosystem20