Age, Gleason scores, incidence of metastases at diagnosis and tumour Ki67-IR at diagnosis for the cases divided on the basis of tumour pAkt-IR and pEGFR-IR scores.

aKruskal-Wallis test. bThe % value refers to the % of cases for the pAkt-IR/pEGFR-IR group in question (i.e. vertical numbers add up to 100%). cķ2 test. dDunn’s Multiple Comparison Test following significant Kruskal-Wallis test. NSNot significant (P>0.05). "pEGFR effect" refers to the comparison between pEGFR-IR <3.2 and ≥3.2 for the given pAkt-IR tranche. For comparisons between pAkt-IR <2.75 and ≥2.75 for pEGFF <3.2 alone, the significance levels for Gleason score, metastases at diagnosis and Ki67-IR (T) were P<0.01c, NSc and P<0.05d, respectively. The corresponding significance levels for pEGFR-IR ≥3.2 alone were P<0.01c, NSc and P<0.01d, respectively.