Proteomic Analysis Reveals Molecular Signatures of Myocardial Infarction and Transverse Aortic Constriction in Aged Mouse Models

Project description: In this study, we performed proteome analyses to identify the key molecules that participate in aged mouse models of MI and transverse aortic constriction (TAC), the latter of which mimics increased left ventricular afterload that in the clinical setting predominantly occurs owing to aortic stenosis or systemic hypertension. B11 represents the tissues of an aged MI mouse. B17 represents the tissues of an aged TAC mouse. B15 represents the tissues of an aged Sham mouse.