Synthesis of Ether Oligomers
收藏NIAID Data Ecosystem2026-03-06 收录
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资源简介:
Hydroxyaromatic aldehydes and ketones were used as building blocks to prepare ether oligomers. An iterative two-step protocol involving Mitsunobu coupling and carbonyl reduction provided a protecting-group-free route with high yields. Activity screening of an 84-member library against proteases led to the discovery of micromolar inhibitors for trypsin, chymotrypsin, and subtilisin.
创建时间:
2016-05-07



