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The N-end rule: functions, mysteries, uses.

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PubMed Central1996-10-29 更新2026-05-02 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC37957/
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The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. Similar but distinct versions of the N-end rule operate in all organisms examined, from mammals to fungi and bacteria. In eukaryotes, the N-end rule pathway is a part of the ubiquitin system. I discuss the mechanisms and functions of this pathway, and consider its applications. IMAGES:
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1996-10-29
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