Transferrin Receptor contributes to PANoptosis in thyroid cancer

PANoptosis is a novel type of cell death triggered by the cross-talk of three types of cell death (necrosis, apoptosis, and pyroptosis). Nevertheless, the molecular mechanisms associated with PANoptosis in thyroid cancer (TC) remain uncharted. Therefore, this study explored the effect of TFRC on PANoptosis in TC cells in vitro. Overall design: This study performed an mRNA-seq for K1 cells from the KD-NC (K1 cells transfected with negative vector) and KD-TFRC (K1 cells transfected with TFRC shRNA) groups