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Gene expression profile at single cell level of bone marrow mononuclear cells from MDS patients with secondary venetoclax-based therapy failure. Gene expression profile at single cell level of bone marrow mononuclear cells from MDS patients with secondary venetoclax-based therapy failure

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NIAID Data Ecosystem2026-05-01 收录
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Myelodysplastic syndromes (MDS) are incurable neoplasms that arise from early hematopoietic stem cells (HSCs). We used single cell RNA sequencing (scRNA-seq) to evaluate mechanisms of resistance to venetoclax-based therapies. Overall design: Bone marrow mononuclear cells were isolated by Fluorescence-activated cell sorting (FACS) and analyzed using scRNAseq.

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2023-08-22
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