data for Protective effect of intra-operative dexmedetomidine infusion combined with epidural blockade on postoperative analgesia and early cognitive dysfunction for elder patients after radical resection of colorectal cancer

Demographic data like age, gender, body mass index (BMI), and clinical data including ASA stage, pathological type and mean operative time were collected. The MMSE score, Ramsay score and Visual Analogue Score (VAS) were all measured at 4h or 2 h, 12 h, 24 h and 48 h after surgery. POCD was defined as the difference between preoperative and postoperative mean MMSE score decline > 2 points [18]. POCD incidence was recorded at 7 d postoperatively. The PCIA pressing time within 48 h, time for patients’ first out of bed activity, first anus exhaust time, hospital stay and complications within 3 months after surgery were also recorded. The follow-up lasted for 3 months.