Mapping of Long-Range Chromatin Interactions using Proximity Ligation Assisted ChIP-seq
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=1ae0f52622b61c2cd22a6853866caec4
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资源简介：
We report Proximity Ligation Assisted ChIP-sequencing (PLAC-seq), a method for comprehensive detection of long-range interactions associated with proteins of interest. PLAC-seq requires up to 500-fold less starting material compared to ChIA-PET and using experimentally determined input as control precisely reveals protein associated interaction upto single-element resolution. Application of PLAC-seq to mouse embryonic stem cells revealed a comprehensive map of regulatory interactions.
提供机构：
Ludwig Institute for Cancer Research
创建时间：
2022-02-20
