Enantioselective Organocatalytic Conjugate Addition of Nitroalkanes to Electrophilic 2-Iminochromenes
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We disclose a new efficient enantioselective organocatalytic conjugate addition method for the preparation of 2-amino-4H-chromenes in high to excellent yields (75–95%) and with high to excellent enantioselectivities (86–97% ee). It is noteworthy that the 2-iminochromene was first disclosed as an active electrophile.
创建时间：
2012-08-03
