Fibrosis-related transcriptome unveils a distinctive matrix remodeling pattern in penetrating but not in stricturing ileal Crohn's disease

Using Nanostring technology and comparative bioinformatics, we analyzed the expression of 760 fibrosis-related genes in 36 ileal surgical specimens, 12 B2(Penetrating) and 24 B3(structuring), the latter including 12 cases with associated stricture(s) (B3s) and 12 without (B3o). nCounter® Fibrosis Consortium Panel was runned in 36 ileal surgical specimens