File S1 - Replication and Meta-Analysis of GWAS Identified Susceptibility Loci in Kawasaki Disease Confirm the Importance of B Lymphoid Tyrosine Kinase (BLK) in Disease Susceptibility

Contains: Table S1. Association of genetic variants in the BLK region and Kawasaki disease in Han Chinese and Korean populations (two independent panels). Table S2. Association of genetic variants in the BLK region and Kawasaki disease in European descent GWAS. Table S3. Analysis the correlation of genotypes of tag SNPs in BLK region with BLK expression levels in transformed B cells in Han Chinese in Bejing. Figure S1. Linkage disequilibrium (LD) structure of region surrounding BLK. Relative position of genes mapping to the BLK region is based on NCBI Build 36. Pairwise LD plots of the estimated statistics of the square of the correlation coefficient (r2) are illustrated with Haploview software. The values in each diamond, which indicate the LD relationship between each pair of SNPs, were derived from genotypes in the Han Chinese GWAS. Red diamonds without a number represent r2 = 1. (PDF)