Sequencing of bacterial genomes has revealed an abundance of prophage sequences in many bacterial species. Since these sequences are accessible, through recombination, to infecting phages, bacteria ca
Each experiment was conducted in duplicate and the two values are shown. The fitness of Qβ was calculated as (Fitness) = Log10 (PFU/ml_max/PFU/ml_0h), where PFU/ml_max is PFU/ml of free phage in which
Protein–protein interactions (PPIs) are critical for organizing molecules in a cell and mediating signaling pathways. Dysregulation of PPIs is often a key driver of disease. To better understand the b
To explore how particularities of a cell-virus system affects viral evolution, we formulate a mathematical model of marine bacteriophage evolution. The intrinsic simplicity of real-life phage-bacteri