LabArchives ELN exports (Yinuo Wang and Dana Klug) for the Open Source Malaria Series 3 paper entitled "Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase"
收藏rdr.ucl.ac.uk2023-11-15 更新2025-03-23 收录
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https://rdr.ucl.ac.uk/articles/dataset/LabArchives_ELN_exports_Yinuo_Wang_and_Dana_Klug_for_the_Open_Source_Malaria_Series_3_paper_entitled_Reaction_hijacking_inhibition_of_Plasmodium_falciparum_asparagine_tRNA_synthetase_/24533407/1
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资源简介:
LabArchives ELN exports for YNW and MNB with experimental details relating to the OSM Series 3 preprint paper titled "Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase". Experiments were performed at UCL. Detailed procedures, characterisation (NMR, LCMS) and raw data files are provided with each reaction write-up for all intermediates and biologically tested final compounds. A list of all OSM Series 3 compounds with associated biology data (MRSA potencies, physicochemical properties, metabolic properties, toxicity) may be also found in OSM3 malaria molecule spreadsheet.
LabArchives 电子实验室笔记(ELN)导出数据,涵盖YNW和MNB实验详情,涉及OSM系列3预印本论文《抑制恶性疟原虫天冬酰胺tRNA合成酶的反应劫持》的相关实验。实验于伦敦大学学院(UCL)进行。每个反应的记录中均包含详细的实验步骤、表征数据(核磁共振NMR、液相色谱-质谱联用LCMS)以及原始数据文件,涉及所有中间体和生物测试的最终化合物。此外,在OSM3疟疾分子电子表格中还可查找到所有OSM系列3化合物及其相关生物学数据(耐甲氧西林金黄色葡萄球菌活性、物理化学性质、代谢特性、毒性)。
提供机构:
University College London



