PROSPER protease substrates and cleavage site data

The collection consists of a biomedical database presented to the community via a web interface (“PROSPER”). The web interface provides the ability for users to perform in silico prediction of protease substrates and their cleavage sites for twenty-four different protease types, covering four major protease families; Aspartic (A), Cysteine (C), Metallo (M) and Serine (S). Within only one and a half years since its inception, PROSPER has attracted more than 4,000 unique visitors worldwide from 66 countries and 5,000 job submissions. As recognition of these important contributions to the protease biology field, PROSPER has been highlighted as a significant bioinformatic tool at the official website of the International Proteolysis Society (IPS).本数据集为一套依托网页界面（"PROSPER"）面向科研社区公开的生物医学数据库。该网页界面支持用户对24种不同蛋白酶的底物及其切割位点开展计算机模拟（in silico）预测，涵盖天冬氨酸蛋白酶（A）、半胱氨酸蛋白酶（C）、金属蛋白酶（M）与丝氨酸蛋白酶（S）四大蛋白酶家族。自上线仅一年半以来，PROSPER已吸引来自全球66个国家的4000余名独立访客，累计提交5000余次分析任务。鉴于其对蛋白酶生物学领域作出的重要贡献，PROSPER已被国际蛋白质水解学会（International Proteolysis Society, IPS）官方网站列为重要的生物信息学工具。