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Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution- in complex with sulphonamide inhibitor 2

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution- in complex with sulphonamide inhibitor 2 Descriptor: 5'-O-{[(2R)-2-hydroxy-3,3-dimethylbutanoyl]sulfamoyl}adenosine, ETHANOL, GLYCEROL, ... Authors: Ciulli, A, Chirgadze, D.Y, Blundell, T.L, Abell, C. Deposit date: 2008-03-29 Release date: 2008-10-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate. Chembiochem, 9, 2008

分辨率为1.8埃的结核分枝杆菌(Mycobacterium Tuberculosis)泛酸合成酶(Pantothenate Synthetase)晶体结构——与磺胺类抑制剂2形成的复合物 描述符:5'-O-{[(2R)-2-羟基-3,3-二甲基丁酰基]磺酰基}腺苷、乙醇(ETHANOL)、甘油(GLYCEROL)等 作者:Ciulli, A、Chirgadze, D.Y、Blundell, T.L、Abell, C 存档日期:2008-03-29 发布日期:2008-10-07 最后修改日期:2023-08-30 实验方法:X射线衍射(X-RAY DIFFRACTION,1.8 Å) 引用文献:《反应中间体类似物对结核分枝杆菌泛酸合成酶的抑制作用》,Chembiochem,第9卷,2008年
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2008-03-29
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