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Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [ChIP-seq]. Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [ChIP-seq]

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NIAID Data Ecosystem2026-03-11 收录
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The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD). Overall design: ]analysis of SNCA promoter interact regions

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2019-12-02
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