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Stereodivergent Access to Polyhydroxylated 10-Azabicyclo[4.3.1]decanes as New Calystegine Analogues

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https://figshare.com/articles/dataset/Stereodivergent_Access_to_Polyhydroxylated_10_Azabicyclo_4_3_1_decanes_as_New_Calystegine_Analogues/2863204
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资源简介:
A rapid and stereodivergent access to polyhydroxylated 10-azabicyclo[4.3.1]decanes as new calystegine analogues by way of a double benzotriazolyl/carbon nucleophile exchange followed by a ring-closing metathesis was achieved. Preliminary evaluation of the new compounds as glucocerebrosidase inhibitors was also performed.
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2009-04-17
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