Global transcriptomic analysis of hepatocyte cells infected with Ebola virus (EBOV)

We performed transcriptomic analysis of a Ebola virus (EBOV) infected hepatocyte cells. We utilized primary human hepatocytes (PHHs), iPSC-derived hepatocytes (iHeps), and immortalized hepatocarcinoma cell line Huh7 cells. Cells were infected with a multiplicity of infection of 10 and harvested after 1 day. Corresponding Mock infected samples were also included in this study. Overall design: Global transcriptomic analysis of 2 donors of PHHs, 3 donors of iHeps, and Huh7 cells were infected with EBOV and harvested 1 day later for analysis. Corresponding mock infected samples were included for each cell type and donor. Triplicate replicates (n=3) were submitted for each donor and cell type (PHH = 6; iHep = 9; Huh7 = 3).