Two new alkaloids identified from herb Delphinium trichophorum French, a famous Tibetan drug “Gebu Dilu”
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A new benzamide derivative alkaloid (1) and a new hetisine-type diterpenoid alkaloid (2) were isolated from D. trichophorum Franch with fourteen known alkaloids compounds (3∼16, including twelve hetisine-type diterpenoid alkaloids), in which three compounds were discovered firstly from genus Delphinium (10, 15, 16) and three compounds were discovered firstly from species D. trichophorum (7, 9, 11). Their structures were elucidated by extensive spectroscopic analyses, including 1D NMR, 2D NMR and ESI-MS/HR ESI-MS techniques, along with their anti-inflammatory activities were evaluated by measuring NO production in LPS-stimulated RAW264.7 cells.
创建时间：
2025-10-14
