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A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene targeted mice
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创建时间：
2015-08-04
相关数据集
Enhanced Innate Response In RB1 deficient Microglia Derived From Retinoblastoma Patient. Enhanced Innate Response In RB1 deficient Microglia Derived From Retinoblastoma Patient
Retinoblastoma (Rb), the most prevalent intraocular malignant tumor in children with global survival rate less than 30%, is mainly caused by the deficiency of the tumor suppressor RB1. A line of evide
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Extrachromosomal circular SUZ12 amplicon dictates retinoblastoma progression through reprogramming H3K27 methylation [CUT&Tag]
Extrachromosomal circular DNA (eccDNA) is double-stranded circular DNA that is derived from but independent of chromosomal DNA. Owing to its nonchromosomal inheritance, eccDNA facilitates the amplific
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RETINOBLASTOMA MICRORNA LANDSCAPE
In this work we examined miRNome expression in 12 samples of retinoblastoma. Present miRNAs show the common working machinery with Rb affecting most of pathways considered hallmarks of cancer. 12 Rb f
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Gene expression profiling of retinoblastoma Y79 cell line treated with scopoletin from Morinda citrifolia in vitro
Retinoblastoma Y79 cell line was treated with scopoletin in vitro and RNA was isolated for microarray experiment to study the changes in the whole gene expression profiling in the Y79 cell line. The s
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Gene expression profiling of retinoblastoma Y79 cell line post EpCAM silencing using siRNA. Homo sapiens
Retinoblastoma Y79 cell line was treated with specific siRNA to silence EpCAM gene expression in vitro and RNA was isolated for microarray experiment to study the changes in the whole gene expression
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